Status:

COMPLETED

Dehydroepiandrosterone (DHEA) in Systemic Lupus Erythematosus (SLE) for Coronary Artery Disease (CAD) Prevention

Lead Sponsor:

University of Michigan

Collaborating Sponsors:

Arthritis Foundation

Conditions:

Systemic Lupus Erythematosus

Eligibility:

FEMALE

18+ years

Phase:

PHASE2

PHASE3

Brief Summary

The purpose of this study is to evaluate the effect of DHEA on endothelial dysfunction in patients with systemic lupus by measuring: 1. changes in brachial artery flow-mediated dilatation (FMD) and 2...

Eligibility Criteria

Inclusion

  • Female
  • Member of the Michigan Lupus Cohort
  • Meet the American College of Rheumatology (ACR) criteria for SLE
  • Premenopausal

Exclusion

  • Smoker
  • Diabetic
  • Prednisone dose \> 10 mg

Key Trial Info

Start Date :

September 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2006

Estimated Enrollment :

13 Patients enrolled

Trial Details

Trial ID

NCT00189124

Start Date

September 1 2003

End Date

July 1 2006

Last Update

May 18 2016

Active Locations (1)

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1

University of Michigan

Ann Arbor, Michigan, United States, 48109