Status:
COMPLETED
Long-Term Cognitive Decline After Coronary Artery Bypass Grafting: is Off-Pump Surgery Beneficial?
Lead Sponsor:
UMC Utrecht
Collaborating Sponsors:
International Anesthesia Research Society (IARS)
Conditions:
Coronary Artery Disease
Cardiopulmonary Bypass
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Coronary artery bypass surgery is associated with postoperative cognitive decline, which has largely been attributed to the use of the heart lung machine. We hypothesized that long-term cognitive outc...
Detailed Description
Background: Coronary artery bypass surgery is associated with postoperative cognitive decline, which has largely been attributed to the use of cardiopulmonary bypass (CPB). A large recent study by Ne...
Eligibility Criteria
Inclusion
- indication for (first-time) coronary artery bypass surgery
- off-pump CABG considered technically possible
Exclusion
- concomitant valve surgery
- unable to complete neuropsychological testing
- life expectancy less than 1 year
Key Trial Info
Start Date :
March 1 1998
Trial Type :
INTERVENTIONAL
End Date :
December 1 2005
Estimated Enrollment :
280 Patients enrolled
Trial Details
Trial ID
NCT00189215
Start Date
March 1 1998
End Date
December 1 2005
Last Update
December 4 2007
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Medical Center, Department of Anesthesiology
Utrecht, Utrecht, Netherlands, 3584 CX