Status:
TERMINATED
ResQ Trial: Impact of an ITD and Active Compression Decompression CPR on Survival From Out-of-Hospital Cardiac Arrest
Lead Sponsor:
Advanced Circulatory Systems
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Heart Arrest
Death, Sudden, Cardiac
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether performing active compression decompression cardiopulmonary resuscitation (ACD-CPR) with an impedance threshold device (ITD) compared to conventional ...
Detailed Description
Despite receiving conventional, standard CPR (S-CPR), most patients who experience out-of-hospital cardiac arrest die prior to arriving at a hospital. At the present time, the hospital discharge rate ...
Eligibility Criteria
Inclusion
- Adult subjects initially presumed or known to be 18 years of age or older
- Subjects who present with out-of-hospital cardiac arrest from presumed cardiac etiology and who receive CPR by Emergency Medical Services (EMS) personnel for at least 1 minute
- Subjects whose airways are managed with a cuffed ET tube, combitube, or laryngeal mask airway or facemask
Exclusion
- Adult subjects presumed or known to be less than 18 years of age
- Subjects with known or likely traumatic injuries causing cardiac arrest or cardiac arrest of presumed noncardiac origin
- Subjects with preexisting Do Not Resuscitate (DNR) orders
- Subjects with signs of obvious clinical death or conditions that preclude the use of CPR
- Family or legal representative request that the subject not be entered into the study
- Subjects experiencing in-hospital cardiac arrest
- Subjects with a recent sternotomy with wound not appearing completely healed (if unknown) or less than 6 months (if known)
- Subjects who received less than 1 minute of CPR by EMS personnel
- Subjects with a complete airway obstruction that cannot be cleared or in whom attempts at advanced airway management are unsuccessful
- Subjects intubated with a leaky or uncuffed advanced airway device or presence of stomas, tracheotomies, or tracheostomies
- Subjects who rearrest and are encountered by EMS within 365 days of the index cardiac arrest
Key Trial Info
Start Date :
October 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2010
Estimated Enrollment :
1653 Patients enrolled
Trial Details
Trial ID
NCT00189423
Start Date
October 1 2005
End Date
July 1 2010
Last Update
December 8 2017
Active Locations (7)
Enter a location and click search to find clinical trials sorted by distance.
1
Site 07: Indianapolis, IN
Indianapolis, Indiana, United States, 46202
2
Site 06: Washtenaw & Livingston Counties, MI
Ann Arbor, Michigan, United States, 48106
3
Site 04: Oakland & Macomb Counties, MI
Royal Oak, Michigan, United States, 48073
4
Site 02: Minneapolis, MN
Minneapolis, Minnesota, United States, 55415