Status:

COMPLETED

Biomechanical Effects of Duloxetine on Bladder and Sphincter Muscle Function in Women in Pure Genuine Stress Incontinence

Lead Sponsor:

Eli Lilly and Company

Collaborating Sponsors:

Boehringer Ingelheim

Conditions:

Urinary Stress Incontinence

Eligibility:

FEMALE

18-75 years

Phase:

PHASE2

Brief Summary

Double-blind placebo-controlled study of the biomechanical effects of duloxetine compared with placebo in the treatment of women with pure genuine stress incontinence

Eligibility Criteria

Inclusion

  • Female
  • Between 18 and 75 years of age
  • Diagnosis of GSI
  • Have discrete episodes of incontinence

Exclusion

  • Positive urine culture at visit 1
  • Use of MAOI
  • Have had continence or urethral surgery
  • Use of anti-incontinence device, vaginal pessaries or medications for the treatment of urinary incontinence
  • Began pelvic floor muscle exercises within 6 months prior to study entry.

Key Trial Info

Start Date :

October 1 2001

Trial Type :

INTERVENTIONAL

End Date :

April 1 2006

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT00190567

Start Date

October 1 2001

End Date

April 1 2006

Last Update

January 26 2007

Active Locations (1)

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For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Monday - Friday from 9:00 AM to 5:00 PM Eastern Time (UTC/GMT - 5hours, EST), or speak with your personal physician

Indianapolis, Indiana, United States, 46202