Status:
COMPLETED
SLIM: Combined Effects of Slo-Niacin and Atorvastatin on Lipoproteins and Inflammatory Markers in Hyperlipidemia
Lead Sponsor:
University of Washington
Collaborating Sponsors:
Upsher-Smith Laboratories
Conditions:
Dyslipidemia
Eligibility:
All Genders
21-75 years
Phase:
PHASE4
Brief Summary
Slo-Niacin and atorvastatin (Lipitor) are both drugs that lower cholesterol. In this research, we will compare the effectiveness of Slo-Niacin and atorvastatin taken alone and together. This study wil...
Detailed Description
Combined niacin and a statin treatment has greater potential value than either agent alone for the dyslipidemia of insulin resistance, obesity and the metabolic syndrome. The efficacy of Slo-Niacin an...
Eligibility Criteria
Inclusion
- LDL-C \> 130 mg/dL
- HDL-C \<= 45 mg/dL in men and \<= 55 mg/dL in women
Exclusion
- history of hypersensitivity to any statin, niacin or aspirin
- diagnosis of diabetes or a fasting glucose \> 125 mg/dL
- hyper or hypothyroidism (unless treatment stable)
- meet other health, medication, and logistical criteria
Key Trial Info
Start Date :
August 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2006
Estimated Enrollment :
64 Patients enrolled
Trial Details
Trial ID
NCT00194402
Start Date
August 1 2003
End Date
January 1 2006
Last Update
August 21 2008
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Northwest Lipid Research Clinic, University of Washington
Seattle, Washington, United States, 98104