Status:
UNKNOWN
Cardioversion vs. Catheter Ablation for Persistent Atrial Fibrillation
Lead Sponsor:
Deutsches Herzzentrum Muenchen
Conditions:
Atrial Fibrillation
Eligibility:
All Genders
20-75 years
Phase:
PHASE4
Brief Summary
The aim of this randomized study is to evaluate the efficacy of two different approaches for conversion of persistent atrial fibrillation, the non-invasive one (external electrical cardioversion) and ...
Detailed Description
This randomized study compares two treatment strategies in patients with persistent atrial fibrillation: Cardioversion vs. catheter ablation. Cardioversion is a low risk standard treatment option for ...
Eligibility Criteria
Inclusion
- Age \>20 years and \<75 years
- documented persistent atrial fibrillation for at least 3 months (documented in at least 2 ECGs or holter-ECGs during the previous 3 months before inclusion and persistent atrial fibrillation in a 7-d-holter)
- documented sufficient anticoagulation for at least 4 weeks before inclusion
Exclusion
- Paroxysmal atrial fibrillation
- NYHA IV (if recompensation is not possible)
- Contraindication for warfarin
- Disturbance of blood coagulation
- Myocardial infarction, PTCA/stenting, bypass-operation, stroke, intracranial bleeding less than 3 months before
- Reversible causes of atrial fibrillation (i.e. hyperthyroidism)
- Pregnancy
- LA-diameter \> 55mm
- LV-function \< 30% EF
- Aortic or mitral stenosis or regurgitation III°-IV°
- Prosthetic valves
Key Trial Info
Start Date :
August 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2009
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT00196209
Start Date
August 1 2005
End Date
December 1 2009
Last Update
March 19 2008
Active Locations (1)
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1
Deutsches Herzzentrum Muenchen
Munich, Germany, 80636