Status:
UNKNOWN
Memantine and Constraint-Induced Language Therapy in Chronic Poststroke Aphasia:A Randomized Controlled Trial
Lead Sponsor:
Gabinete Berthier y Martínez
Collaborating Sponsors:
H. Lundbeck A/S
Conditions:
Aphasia
Stroke
Eligibility:
All Genders
18-69 years
Phase:
PHASE4
Brief Summary
* Aphasia, the loss or impairment of language caused by brain damage, is one of the most devastating cognitive impairments of stroke. Aphasia can be treated with combination of speech-language therapy...
Detailed Description
* The efficacy of drugs that act on glutamate such as the N-methyl-D-aspartic acid (NMDA) receptor antagonist memantine requires to be explored in this population. The rationale for using memantine in...
Eligibility Criteria
Inclusion
- Chronic aphasia of more than one year duration
- Must be able to complete protocol
Exclusion
- Dementia
- Major psychiatric illness
- Severe global aphasia (precludes participation in constraint-induced language therapy)
Key Trial Info
Start Date :
March 1 2005
Trial Type :
INTERVENTIONAL
End Date :
September 1 2005
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00196703
Start Date
March 1 2005
End Date
September 1 2005
Last Update
September 20 2005
Active Locations (1)
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1
Gabinete Berthier y Martínez and Centro de Investigaciones Médico-Sanitarias (CIMES) University of Malaga
Málaga, Malaga, Spain, 29001