Status:
COMPLETED
Nutrition, Immunology and Epidemiology of Tuberculosis
Lead Sponsor:
Harvard School of Public Health (HSPH)
Collaborating Sponsors:
Muhimbili University of Health and Allied Sciences
Conditions:
Tuberculosis
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The purpose of this study is to determine the efficacy of micronutrient supplementation among patients with active tuberculosis, half of who are co-infected with HIV-1
Detailed Description
Tuberculosis (TB) remains the single most common infectious disease cause of mortality. We propose to examine the inter- relationships of nutrition, immunology, and epidemiology with respect to TB in ...
Eligibility Criteria
Inclusion
- Men and women, age 18 to 60 years inclusive
- At least two positive sputum smears for tuberculosis
- Intention to stay in Dar-es-Salaam for at least 2 years after the start of TB therapy
- Subjects who grant informed consent to participation
Exclusion
- Karnofsky score \< 40%
- Hemoglobin \< 8.5 g/dl
- Having had treatment for TB exceeding 4 weeks in the last 5 years
- Pregnant women
Key Trial Info
Start Date :
March 1 2000
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2004
Estimated Enrollment :
876 Patients enrolled
Trial Details
Trial ID
NCT00197704
Start Date
March 1 2000
End Date
May 1 2004
Last Update
November 11 2010
Active Locations (1)
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1
Harvard School of Public Health
Boston, Massachusetts, United States, 02115