Status:
COMPLETED
Clinical Trial With Ziprasidone for the Treatment of Psychiatric Pathology Associated to Alcoholism
Lead Sponsor:
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Collaborating Sponsors:
Pfizer
Conditions:
Depression
Anger
Eligibility:
All Genders
18-65 years
Phase:
PHASE3
Brief Summary
Alcohol dependent patients show comorbid psychiatric symptoms, related to malfunction of dopamine, norepinephrine and serotonin neurotransmission, during early recovery. Ziprasidone can improve malfun...
Detailed Description
60 alcohol-dependent patients will be included, once finished alcohol detoxification treatment.Thirty patients will receive ziprasidone treatment, in progressively increasing doses, starting from 40 m...
Eligibility Criteria
Inclusion
- DSM-IV-TR criteria for alcohol dependence disorder
- Age between 18 -65 years old.
- Score 7 or higher in the GHQ-28 scale.
Exclusion
- More than 30 days without drinking alcohol.
- Severe medical disorders.
- Psychotic or bipolar disorders severely decompensated requiring antipsychotic medication.
- Opiate, cocaine or benzodiazepine dependence disorders, requiring more than one week of detoxification treatment.
- Pregnant or lactating women
Key Trial Info
Start Date :
October 1 2004
Trial Type :
INTERVENTIONAL
End Date :
April 1 2007
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00197951
Start Date
October 1 2004
End Date
April 1 2007
Last Update
April 23 2007
Active Locations (1)
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1
Unidad de Conductas Adictivas//Servicio de Psiquiatría//Hospital de la Santa Creu i Sant Pau
Barcelona, Barcelona, Spain, 08025