Status:

COMPLETED

Bipolar vs Monopolar Transurethral Resection of the Prostate (TURP)

Lead Sponsor:

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Collaborating Sponsors:

Gyrus ACMI, Inc.

Conditions:

BPH

Benign Prostatic Hyperplasia

Eligibility:

MALE

50-85 years

Phase:

PHASE4

Brief Summary

This study will prospectively evaluate a new electrosurgical procedure (bipolar transurethral prostatectomy) in men with symptomatic benign prostatic hyperplasia.

Detailed Description

The purpose of this study is to demonstrate that the Bipolar TURP using the Vista Controlled Tissue Resection System is safe and efficacious as a surgical treatment for men with symptomatic BPH, allow...

Eligibility Criteria

Inclusion

  • Symptomatic benign prostatic hyperplasia including patients with acute urinary retention;
  • Peak urinary flow rate \< 12 ml/sec;
  • American Urological Association (AUA) symptom score \> 12.

Exclusion

  • Previous open or transurethral prostatic surgery;
  • History of urethral stricture;
  • Failure to discontinue alpha-adrenergic blocking agents for at least 14 days prior to surgery;
  • Failure to discontinue 5-alpha reductase inhibitor for at least 1 month prior to surgery;
  • Patient interested in future fertility;
  • Patient with known neurogenic bladder dysfunction;
  • Untreated urinary tract infection;
  • American Society of Anesthesiologist (ASA) Class \>III;
  • Patients requiring anticoagulation with Coumadin or Heparin;
  • Patient unable or unwilling to comply with follow-up schedule.

Key Trial Info

Start Date :

May 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2008

Estimated Enrollment :

43 Patients enrolled

Trial Details

Trial ID

NCT00199550

Start Date

May 1 2004

End Date

June 1 2008

Last Update

July 29 2008

Active Locations (6)

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Page 1 of 2 (6 locations)

1

Alberta Urology Institute Research Centre

Edmonton, Alberta, Canada, T5H 4B9

2

Prostate Centre at Vancouver General Hospital

Vancouver, British Columbia, Canada, V5Z 3J5

3

Can-Med Clinical Research Inc

Victoria, British Columbia, Canada, V8R 6T9

4

Hamilton District Urology Associaton

Hamilton, Ontario, Canada, L8N 1T8