Status:
COMPLETED
Peripheral Effects of Exercise on Cardiovascular Health (STRRIDE I)
Lead Sponsor:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Cardiovascular Diseases
Heart Diseases
Eligibility:
All Genders
40-69 years
Phase:
PHASE2
Brief Summary
To investigate the separate effects of the amount of exercise and exercise intensity on cardiovascular risk factors in overweight men and women with mild to moderate dyslipidemia.
Detailed Description
BACKGROUND: Substantial evidence supports a favorable relationships between cardiovascular fitness, physical activity and cardiovascular health. In particular, it is well established that increased l...
Eligibility Criteria
Inclusion
- Inclusion criteria: age 40 to 65 years, sedentary (exercise less than two times per week), overweight or mildly obese (BMI 25 to 35 kg/m2) with mild to moderate lipid abnormalities (either LDL cholesterol 130 to 190 mg/dl; or HDL cholesterol \< 40 mg/dl for men, or 5 \< 45 mg/dl for women). Women were postmenopausal.
- Exclusion criteria: diabetes; hypertension; other metabolic or musculoskeletal diseases; current use of or intent to diet; use of confounding medications; overt presence of coronary heart disease; or unwillingness to be randomized to any group.
Exclusion
Key Trial Info
Start Date :
September 1 1998
Trial Type :
INTERVENTIONAL
End Date :
April 1 2009
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00200993
Start Date
September 1 1998
End Date
April 1 2009
Last Update
April 14 2009
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