Status:

COMPLETED

Effects of Bronchodilators in Mild Chronic Obstructive Pulmonary Disease (COPD)

Lead Sponsor:

Queen's University

Conditions:

Chronic Obstructive Pulmonary Disease (COPD)

Eligibility:

All Genders

40-80 years

Phase:

PHASE4

Brief Summary

In people with mild COPD, the ability to exhale air from the lungs is partly limited because of narrowing and collapse of the airways. This results in the trapping of air within the lungs and over-dis...

Detailed Description

In people with mild COPD, the ability to exhale air from the lungs is partly limited because of narrowing and collapse of the airways. This results in the trapping of air within the lungs and over-dis...

Eligibility Criteria

Inclusion

  • diagnosis of mild COPD OR healthy control subjects
  • 40-80 years old
  • able to perform all study procedures
  • Smoking history \> 10 pack years (for mild COPD) or smoking history \< 10 pack years (for healthy control subjects)

Exclusion

  • allergy to atrovent
  • history of asthma, atopy or nasal polyps
  • Oxygen desaturation \< 80 % during exercise
  • recent history of CAD (under a year) or any significant diseases that could contribute to dyspnea or exercise limitation

Key Trial Info

Start Date :

July 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2008

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT00202176

Start Date

July 1 2005

End Date

December 1 2008

Last Update

April 19 2011

Active Locations (1)

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1

Respiratory Investigation Unit

Kingston, Ontario, Canada, K7L 2V7