Status:
UNKNOWN
Perioperative Effect of Atenolol on Cytokine Profiles
Lead Sponsor:
Saini Foundation
Collaborating Sponsors:
Medtronic - MITG
Conditions:
Surgery
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Studies have shown that beta-blockers such as atenolol when given in the perioperative period reduce morbidity and mortality. One study showed that atenolol given just during the surgery period, seeme...
Eligibility Criteria
Inclusion
- elective abdominal, orthopedic, or gynecologic surgery
- ability to give informed consent
- ability to tolerate beta-blocker therapy
- ability to comply with follow-up requirements
Exclusion
- currently receiving beta-blocker therapy
- EKG documented 2nd or 3rd degree heart block
- EKG documented sinus bradycardia
- Serum creatinine \> 2.0
- current treatment asthma
- history of rheumatoid arthritis
- history of Crohn's disease
- history of lupus
- history of inflammatory cancer
Key Trial Info
Start Date :
November 1 2002
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2008
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00202358
Start Date
November 1 2002
End Date
September 1 2008
Last Update
June 17 2008
Active Locations (1)
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1
Cape Cod Hospital
Hyannis, Massachusetts, United States, 02601