Status:
COMPLETED
Relationship Between Succinate Dehydrogenase Mutations and High-Altitude Illness
Lead Sponsor:
Société Française de Cardiologie
Conditions:
Altitude Intolerance
High-Altitude Illness
Eligibility:
All Genders
18-65 years
Brief Summary
This study is is the first step of a full study named CHEMOGENE because it explores the genetic determinant of an alteration of the chemoreflex. This reflex determines hyperventilation when the pressu...
Detailed Description
Subjects are selected at an outpatient clinic specialised in the diagnosis of tolerance to altitude, where the chemoreflex is analyzed during a bicycle exercise performed with a oxygen deprived air si...
Eligibility Criteria
Inclusion
- Chemoreflex sensitivity measured (normal or pathologic)
- Journey to high-altitude (well tolerated or with a severe disease such as pulmonary edema or cerebral edema)
Exclusion
- Asthma,
- Arterial hypertension,
- Drug treatment
Key Trial Info
Start Date :
March 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2006
Estimated Enrollment :
83 Patients enrolled
Trial Details
Trial ID
NCT00202683
Start Date
March 1 2005
End Date
December 1 2006
Last Update
May 17 2007
Active Locations (1)
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1
Centre d'Investigation Clinique, Hopital Pompidou
Paris, France, 75908