Status:
UNKNOWN
Study on Amino Acid Uptake in Brain Tumors
Lead Sponsor:
University Hospital Muenster
Conditions:
Brain Neoplasms
Eligibility:
All Genders
Phase:
PHASE2
Brief Summary
The purpose of this study is to determine the uptake of the amino acid O-(2-\[F-18\]Fluorethyl)-L-tyrosin (FET) in human brain tumors using positron emission tomography. A comparison to MRI and histop...
Detailed Description
Radioactively labelled amino acids have been used for years to delineate primary brain tumors and for the early detection of tumor recurrence. Positron emission tomography studies indicate that the ex...
Eligibility Criteria
Inclusion
- Patients with suspected primary brain tumors
- CT or MRI showing lesion of \>= 2,5 cm
- Any age; parents informed consent in children available
- Karnofsky-Index \>= 20 %
- Referral by Depts. of Neurology, Neuro-Oncology, Neurosurgery, or Pediatric Neurology at the UKM
- Biopsy and/or surgery planned
- Patient is able to lie during the PET scan for 50 minutes without moving • Patient must be able to give informed consent; signature must be present before the PET scan
Exclusion
- Pregnancy or breast feeing
- Patients, who by psychiatric disease are not able to give informed consent
- Complete renal failure
- Inclusion to other studies according to § 23 of the German radiation protection law
Key Trial Info
Start Date :
January 1 2004
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00204295
Start Date
January 1 2004
Last Update
September 14 2006
Active Locations (1)
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1
Department of Nuclear Medicine, University Hospital Muenster
Münster, North Rhine-Westphalia, Germany, D-48149