Status:

COMPLETED

Soy Isoflavones and Breast Cancer Risk Reduction

Lead Sponsor:

The University of Texas Medical Branch, Galveston

Collaborating Sponsors:

National Cancer Institute (NCI)

National Center for Research Resources (NCRR)

Conditions:

Breast Cancer

Eligibility:

FEMALE

30-42 years

Phase:

PHASE2

Brief Summary

Soy consumption has been associated with reduced risk for developing breast cancer. Soy contains isoflavones which are weak estrogens. The roles of soy isoflavones in reducing breast cancer risk are c...

Detailed Description

This is a randomized, double-blind study, with two arms and 100 women in each arm. Premenopausal women will be recruited and randomly allocated to take one of the two different dietary supplements in ...

Eligibility Criteria

Inclusion

  • healthy premenopausal women
  • 30 to 42 years old
  • normal mammograms
  • regular menstrual cycles

Exclusion

  • abnormal mammograms
  • first degree relatives with breast cancer
  • pregnant or lactating
  • peri- or post-menopause
  • breast augmentation, reduction or lifting
  • on oral contraceptive medications or exogenous hormones
  • medically prescribed diets
  • allergic reaction to soy products

Key Trial Info

Start Date :

April 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 31 2023

Estimated Enrollment :

197 Patients enrolled

Trial Details

Trial ID

NCT00204490

Start Date

April 1 2004

End Date

May 31 2023

Last Update

May 16 2024

Active Locations (1)

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General Clinical Reserach Center, The University of Texas Medical Branch

Galveston, Texas, United States, 77555-0264