Status:
COMPLETED
The Role of GER in Exercise Triggered Asthma
Lead Sponsor:
University of Utah
Collaborating Sponsors:
PriCara, Unit of Ortho-McNeil, Inc.
Conditions:
Asthma
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
PHASE3
Brief Summary
HYPOTHESIS Gastroesophageal reflux is a major contributor to exercise-triggered asthma. Two groups of patients will be studied: those with asthma who have difficulty with exertion, those without ast...
Detailed Description
PRIMARY OBJECTIVE To determine whether patients with exercise-triggered asthma experience GER during exercise. SECONDARY OBJECTIVES To determine whether the exercise-induced GER within the subjects...
Eligibility Criteria
Inclusion
- Exercise-triggered asthmatics - defined as asthmatics with exertion as their primary exacerbating factor and experiencing less than two episodes of classic gastroesophageal reflux a week.
Exclusion
- Exclusion criteria will be the following:
- Severe asthma (recent or repeated hospitalizations)
- Severe angina, cardiac arrhythmia's, heart failure, prior MI
- Respiratory illness e.g. COPD
- Inability to receive therapy/pH probe
- Pregnancy
- Minors, prisoners, individuals unable to give informed consent
- Prior upper GI surgery (gastrectomy, etc)
Key Trial Info
Start Date :
October 1 2000
Trial Type :
INTERVENTIONAL
End Date :
September 1 2005
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT00204672
Start Date
October 1 2000
End Date
September 1 2005
Last Update
September 20 2005
Active Locations (1)
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1
University of Utah
Salt Lake City, Utah, United States, 84132