Status:
COMPLETED
Dopaminergic, Functional, Structural, and Cognitive Disturbances in First-episode Schizophrenia
Lead Sponsor:
Birte Glenthoj
Collaborating Sponsors:
University of Copenhagen
Glostrup University Hospital, Copenhagen
Conditions:
Schizophrenia
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
We wanted to compare dopamine D2 receptor activity, brain structure, brain function, sensory gating and cognition in neuroleptic-naive schizophrenic patients and matched healthy controls. Additionally...
Detailed Description
31 neuroleptic-naive schizophrenic patients and 25 matched controls were recruited from the greater Copenhagen area. The patients were randomized to treatment with either low doses of the typical anti...
Eligibility Criteria
Inclusion
- For patients: Clinical diagnosis of schizophrenia.
- The controls were matched to the patients.
Exclusion
- Patients: Previous antipsychotic treatment, patients who were compulsorily hospitalised or deemed in acute need of medication, mental retardation
- Controls: psychiatric diagnosis, psychiatric diagnosis in first-degree relatives, drug abuse, mental retardation
Key Trial Info
Start Date :
January 1 1998
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2010
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT00206960
Start Date
January 1 1998
End Date
September 1 2010
Last Update
September 19 2011
Active Locations (6)
Enter a location and click search to find clinical trials sorted by distance.
1
Neurobiology Research Unit, University of Copenhagen, Rigshospitalet
Copenhagen, Denmark, DK-2100
2
Dept. of Nuclear Medicine, University of Copenhagen, Bispebjerg Hospital
Copenhagen NV, Denmark, DK-2400
3
University of Copenhagen, Dept. F, Bispebjerg Hospital
Copenhagen NV, Denmark, DK-2400
4
University of Copenhagen, Dept. of Psychiatry E, Bispebjerg Hospital
Copenhagen NV, Denmark, DK-2400