Status:

COMPLETED

Liquid Meal Replacements in Conjunction With Lifestyle Intervention in Overweight Adolescents

Lead Sponsor:

Boston Medical Center

Conditions:

Overweight

Obesity

Eligibility:

All Genders

12-18 years

Phase:

PHASE1

Brief Summary

In this 3-month pilot study, we will introduce to 40 adolescents "at risk for overweight" (i.e., a BMI/age \>85th percentile) a structured meal plan consisting of meal replacements, fruits, vegetables...

Detailed Description

In this 3-month pilot study, we will introduce to 40 adolescents "at risk for overweight" (i.e., a BMI/age \>85th percentile), a structured meal plan consisting of meal replacements, fruits, vegetable...

Eligibility Criteria

Inclusion

  • BMI \>85th% for age and sex
  • Weight gain over the last 6 months of \>5% than expected on the growth curve
  • 12-17 years of age

Exclusion

  • Subjects with intolerance to dairy products (e.g., lactose intolerance) will be excluded from entering into the study.
  • Subjects must not have a history of clinically significant cardiac disease, congenital heart disease, any clinically significant abnormal cardiac condition, or be known to have a clinically significantly abnormal ECG. Specifically excluded conditions include coronary artery disease, clinically significant cardiac arrhythmias, and congestive heart failure.
  • Subjects must not have a history of anorexia nervosa, untreated hypothyroidism (TSH greater than 4.0 mU/L for a second generation test), malignancy, pathophysiologic or genetic syndromes associated with obesity (i.e., Cushing's syndrome, Turner's syndrome, Prader Willi syndrome), major psychiatric illness such as bi-polar disorder, ADD, major depression, bulimia, schizophrenia, or psychosis.
  • Subjects may not participate in any weight management program, except for that in this study, during this pilot. Subjects may not use prescription or over-the-counter (or herbal) weight control medication during the trial.
  • Subjects must not have a history of alcohol or drug addiction or substance abuse within the previous 2 years.

Key Trial Info

Start Date :

April 1 2003

Trial Type :

INTERVENTIONAL

End Date :

January 1 2009

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00207519

Start Date

April 1 2003

End Date

January 1 2009

Last Update

February 11 2009

Active Locations (1)

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1

Boston University Medical

Boston, Massachusetts, United States, 02118