Status:

UNKNOWN

Trial of Filgrastim Versus Placebo Following Allogeneic Bone Marrow Transplantation

Lead Sponsor:

Centre National de Greffe de Moelle Osseuse

Conditions:

Graft vs Host Disease

Eligibility:

All Genders

16-45 years

Phase:

PHASE3

Brief Summary

The effect of haematopoietic growth factors on neutrophil recovery after allogeneic bone marrow transplantation is well recognized. Recent laboratory studies demonstrated that these cytokines may also...

Eligibility Criteria

Inclusion

  • Age: \> 16 years and \< 46 years
  • Geno-identical allogeneic bone marrow transplantation
  • Myeloablative conditioning regimen
  • Haematological malignancies and acquired aplastic anemia
  • Written and informed consent

Exclusion

  • ECOG performance score \> 2
  • T-cell depletion
  • Serum creatinine level \> 133 µmol/L
  • Abnormal liver function
  • Positive HIV test
  • Pregnant women

Key Trial Info

Start Date :

July 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

160 Patients enrolled

Trial Details

Trial ID

NCT00207792

Start Date

July 1 2005

Last Update

November 6 2007

Active Locations (1)

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1

Centre National de Greffe de Moelle Osseuse

Tunis, Tunisia