Status:
COMPLETED
Treatment of Reduced Heart Rate Variability Associated With Major Depression With Electroconvulsive Therapy
Lead Sponsor:
Emory University
Collaborating Sponsors:
The Dana Foundation
Conditions:
Major Depressive Disorder
Eligibility:
All Genders
18-90 years
Brief Summary
The purpose of this study is to evaluate alterations in sympathetic tone in patients with major depression with and without ischemic heart disease and then to reevaluate these patients after 8 treatme...
Detailed Description
There is considerable evidence that patients with ischemic heart disease (IHD) and concurrent major depression have a less favorable prognosis than patients with IHD alone. Indeed, a number of recent ...
Eligibility Criteria
Inclusion
- \-
Exclusion
- Patients will not be accepted into the study if they abuse alcohol or drugs.
- Patients will be excluded from the study if they have had an MI within the past three months, unstable crescendo angina or ongoing warfarin treatment
- Patients also will not be accepted into the study if ECT will be harmful to them. These patients include:
- those who have had a recent MI (\<3 months)
- those who have an infection of the brain,
- those who have a condition in which there is increased intracranial pressure (e.g. a brain tumor)
- those who cannot tolerate general anesthesia.
- Any patient with a current DSM-IV Axis I diagnosis other than major depression will be excluded from the study.
Key Trial Info
Start Date :
November 1 1998
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2005
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00209066
Start Date
November 1 1998
End Date
April 1 2005
Last Update
November 19 2013
Active Locations (1)
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1
Emory University School of Medicine
Atlanta, Georgia, United States, 30322