Status:

UNKNOWN

Effect of Escitalopram vs. Reboxetine on Gastro-intestinal Sensitivity of Patients With Major Depressive Disorder

Lead Sponsor:

Hospital Universitari Vall d'Hebron Research Institute

Conditions:

Major Depression

Pain

Eligibility:

All Genders

18-64 years

Phase:

PHASE4

Brief Summary

Patients with major depressive disorder (MDD) commonly have many gastrointestinal complaints. Gastrointestinal pain is classified into 2 categories: visceral and somatic pain. The main aim of this stu...

Eligibility Criteria

Inclusion

  • MDD according with DSM-IV-TR
  • Hamilton depression scale \> 21

Exclusion

  • history of gastrointestinal illness
  • history of escitalopram, citalopram or reboxetine allergy.
  • history of escitalopram, citalopram or reboxetine resistant depression.
  • other axis I psychiatric disorder.
  • a punctuation \> 2 on the suicide item of the Ham-D.
  • history of ECT during the past 6 months.
  • pharmacological failure of the present depressive episode.
  • pregnancy or nursing.
  • treatment with drugs that may interact with study medication.

Key Trial Info

Start Date :

September 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2011

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT00209807

Start Date

September 1 2005

End Date

April 1 2011

Last Update

May 27 2010

Active Locations (1)

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1

Hospital Universitari vall d'Hebron

Barcelona, Catalonia, Spain, 08036