Status:

COMPLETED

Potential Impact (Benefit) of Preventative Treatment With Topamax on the Effectiveness of Axert in the Acute Treatment of Migraine

Lead Sponsor:

Janssen-Ortho LLC

Collaborating Sponsors:

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Conditions:

Migraine

Classic Migraine

Eligibility:

All Genders

18-65 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to evaluate the impact of topiramate (migraine prevention medicine) on the effectiveness of almotriptan malate (acute migraine medicine) when treating acute migraine heada...

Detailed Description

Migraine afflicts greater than 28 million adults in the United States. Acute treatments, such as almotriptan malate, target the symptoms of a migraine attack. Preventive treatments, such as topiramate...

Eligibility Criteria

Inclusion

  • Have a history of migraine headaches for at least 6 months
  • Experience 3-12 migraines per month
  • Able to take oral medication
  • Able to complete the electronic diary (Personal Digital Assistant-PDA).

Exclusion

  • You will not be able to participate in the study if you previously discontinued Topiramate or Almotriptan because it did not make you feel better or it made you feel different
  • Have 15 or more headache days a month
  • Experience migraine aura without a headache
  • Already on a migraine preventative medicine.

Key Trial Info

Start Date :

June 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2007

Estimated Enrollment :

406 Patients enrolled

Trial Details

Trial ID

NCT00210496

Start Date

June 1 2005

End Date

June 1 2007

Last Update

May 17 2011

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