Status:

COMPLETED

An Open-Label Extension Study of the Effectiveness and Safety of the Investigational Compound RWJ-333369 in Patients With Epilepsy

Lead Sponsor:

SK Life Science, Inc.

Conditions:

Epilepsy

Epilepsies, Partial

Eligibility:

All Genders

18-70 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to evaluate the effectiveness and safety of the novel compound RWJ-333369 in reducing the frequency of seizures in patients with epilepsy.

Detailed Description

333369EPY2006 is the open-label extension study that follows the double-blind study 333369EPY2003. In an open label study such as 333369EPY2006, both the physician and the patient know the name of the...

Eligibility Criteria

Inclusion

  • Patients must complete Visit 8 (Day 112) of the double-blind treatment phase of Study EPY-2003 to be eligible for entry into the open-label treatment phase of Study EPY-2006.

Exclusion

  • Patients who have seizures that cannot be quantitated accurately
  • Patients with a history of nonepileptic seizures, serious systemic disease, progressive neurologic disorder, a major psychiatric disorder, status epilepticus in the past 3 months, vagal nerve stimulation discontinuation within the past 3 months
  • Patients with a history of drug or alcohol abuse within the past 2 years
  • Patients currently taking felbamate, vigabatrin, or tricyclic antidepressants
  • and patients who are pregnant or nursing.

Key Trial Info

Start Date :

May 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2010

Estimated Enrollment :

421 Patients enrolled

Trial Details

Trial ID

NCT00210522

Start Date

May 1 2005

End Date

June 1 2010

Last Update

January 24 2013

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