Status:

COMPLETED

Functional Magnetic Resonance Imaging (fMRI) for the Study of Response Inhibition, and Face and Linguistic Processing in Autism

Lead Sponsor:

Icahn School of Medicine at Mount Sinai

Conditions:

Autism

Asperger's Syndrome

Eligibility:

All Genders

18-50 years

Brief Summary

This study investigates face processing, response inhibition and phoneme processing in autistic adults by fMRI.

Detailed Description

Fifteen adult outpatients with high functioning autism or Asperger's Syndrome will be recruited. Fifteen healthy volunteers matched for age and IQ will also be recruited. Participants will undergo an ...

Eligibility Criteria

Inclusion

  • Age range of 18-50 years old
  • Diagnosis: autism spectrum disorder by Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) and Autism Diagnostic Interview - Revised (ADI-R)
  • Intelligence quotient (IQ) \> 80
  • Outpatients

Exclusion

  • Subjects with epilepsy
  • Subjects with history of schizophrenia, schizoaffective disorder or other Axis 1 mental disorders, such as bipolar disorder
  • Subjects reporting history of encephalitis, phenylketonuria, tuberous sclerosis, fragile X syndrome, anoxia during birth, neurofibromatosis, hypomelanosis of Ito, hypothyroidism, Duchenne muscular dystrophy, and maternal rubella
  • Subjects who have received depot neuroleptic medication, or other psychoactive drugs within the past 5 weeks.

Key Trial Info

Start Date :

November 1 2004

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2012

Estimated Enrollment :

71 Patients enrolled

Trial Details

Trial ID

NCT00211783

Start Date

November 1 2004

End Date

June 1 2012

Last Update

June 28 2012

Active Locations (1)

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Mount Sinai School of Medicine

New York, New York, United States, 10029