Status:

COMPLETED

PEAK Study (Physical Exercise and Activity in Kids)

Lead Sponsor:

The Hospital for Sick Children

Collaborating Sponsors:

Canadian Institutes of Health Research (CIHR)

Conditions:

Juvenile Idiopathic Arthritis

Eligibility:

All Genders

8-16 years

Phase:

PHASE2

Brief Summary

The objectives of this study are to study the effect of formal exercise training on motor function and overall physical fitness in children with arthritis. A 12-week comprehensive exercise program wil...

Detailed Description

Childhood arthritis is a common and often debilitating disease. Children with arthritis are less active than their peers, and consequently they often have poor physical fitness. This study follows up ...

Eligibility Criteria

Inclusion

  • Age 8 - 16 years.
  • Diagnosis of Juvenile Idiopathic Arthritis - based on the revised Durban criteria.
  • Polyarticular or pauciarticular course.
  • Stable Disease - on a stable dose of NSAID, and if applicable methotrexate or other second line agents - in the preceding month, and judged by the attending rheumatologist to be clinically stable and unlikely to need a change in medication over the course of the trial.
  • Medications. There are no restrictions on medication use for this study; however, every effort is made to keep medication dosage stable over the course of study.

Exclusion

  • Co-morbidity with cardiac, pulmonary or metabolic disease.
  • Moderate or severe hip pain while walking (as judged by the patient and scored on a 4 point scale) or active systemic symptoms (fever, rash).
  • Children who engage in more than 3 hours of structured extracurricular physical activity weekly may not show additional gains from fitness training and, therefore, are not studied. Children are not otherwise excluded from the study if currently attending a physiotherapy pool program with emphasis on joint range of motion and stretching.
  • Children who are unable to cooperate with testing procedures.

Key Trial Info

Start Date :

August 1 2002

Trial Type :

INTERVENTIONAL

End Date :

November 1 2005

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT00213187

Start Date

August 1 2002

End Date

November 1 2005

Last Update

December 18 2013

Active Locations (1)

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1

The Hospital for Sick Children

Toronto, Ontario, Canada, M5G 1X8