Status:
COMPLETED
A Dose Finding Study of Remifentanil and Propofol for Lumbar Punctures in Children
Lead Sponsor:
The Hospital for Sick Children
Conditions:
Hematologic Diseases
Neoplasms
Eligibility:
All Genders
4-11 years
Phase:
PHASE1
PHASE2
Brief Summary
This study will examine whether the combination of two anaesthetic medications, propofol and remifentanil, is suitable for short duration surgical procedures, providing a shorter recovery time and few...
Detailed Description
Propofol is the primary medication used by anesthesiologists at HSC to provide sedation for lumbar puncture. Propofol provides amnesia, anxiolysis, and hypnosis, but because propofol has no analgestic...
Eligibility Criteria
Inclusion
- Clinical diagnosis of a hemato-oncological disorder
- Scheduled to undergo a lumbar puncture
- Aged 4-11 years
- Male or female
- Unpremedicated
- Willing and able to provide informed consent (or informed consent by parents)
Exclusion
- Children who are known or suspected to be difficult to ventilate by face mask
- Children who are deemed medically unfit to receive either of the two study medications
- Children who are obese (weight for height \> 95th percentile,
- Children who do not have an indwelling intravenous line
Key Trial Info
Start Date :
September 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2008
Estimated Enrollment :
64 Patients enrolled
Trial Details
Trial ID
NCT00213239
Start Date
September 1 2005
End Date
January 1 2008
Last Update
December 2 2019
Active Locations (1)
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1
The Hospital for Sick Children
Toronto, Ontario, Canada, M5G 1X8