Status:

COMPLETED

Seroquel on Glucose Metabolism

Lead Sponsor:

AstraZeneca

Conditions:

Schizophrenia

Eligibility:

All Genders

18-65 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to determine whether six months treatment with the antipsychotic medicine Seroquel (quetiapine) may affect the schizophrenic patient's glucose metabolism

Eligibility Criteria

Inclusion

  • In- or outpatients with schizophrenia, 18-65 years old, requiring a change in treatment due to insufficient efficacy or tolerability and giving signed informed consent.

Exclusion

  • Known diabetes mellitus, high HbA1c, fasting plasma glucose and/or high 2h glucose-OGTT.
  • Previous use of atypicals (3 months) or other medications that might influence glucose metabolism
  • Contraindications or non-responsiveness for any of the treatments or other safety issues
  • Expected non-compliance to treatment and/or study procedures

Key Trial Info

Start Date :

April 1 2004

Trial Type :

INTERVENTIONAL

End Date :

October 1 2005

Estimated Enrollment :

572 Patients enrolled

Trial Details

Trial ID

NCT00214578

Start Date

April 1 2004

End Date

October 1 2005

Last Update

January 4 2013

Active Locations (70)

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Page 1 of 18 (70 locations)

1

Research Site

Burgas, Bulgaria

2

Research Site

Rousse, Bulgaria

3

Research Site

Sofia, Bulgaria

4

Research Site

Sofia- Novi Iskar, Bulgaria