Status:
COMPLETED
Effectiveness of Modafinil and D-amphetamine in Treating Cocaine Dependent Individuals
Lead Sponsor:
The University of Texas Health Science Center, Houston
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Cocaine-Related Disorders
Eligibility:
All Genders
18-55 years
Phase:
PHASE2
Brief Summary
Cocaine dependence is a major public health problem; an effective primary treatment for cocaine dependent individuals has yet to be found. The purpose of this study is to examine the effects of d-amph...
Detailed Description
Cocaine is a strong central nervous system stimulant that is widely abused throughout the United Sates. Due to its widespread use, it is important to develop an effective treatment for cocaine depende...
Eligibility Criteria
Inclusion
- Meets Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-IV (SCID) criteria for cocaine abuse or dependence
- In general good health. Individuals who are HIV-positive will not be excluded if in good general health, unless medication interactions exist.
Exclusion
- Meets diagnostic criteria for psychiatric disorders, including other forms of drug dependence, other than nicotine
- Current cardiovascular disease, as determined by an electrocardiogram
- On probation or parole if the circumstances do not allow study completion or if ethical constraints of supervision do not allow confidentiality
- Previously received treatment with d-amphetamine, modafinil, or aripiprazole
- Currently receiving prescribed medication
Key Trial Info
Start Date :
March 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2012
Estimated Enrollment :
73 Patients enrolled
Trial Details
Trial ID
NCT00218062
Start Date
March 1 2006
End Date
January 1 2012
Last Update
June 21 2017
Active Locations (1)
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1
University of Texas Health Science Center
Houston, Texas, United States, 77030