Status:
COMPLETED
Treatment of Opioid/Heroin Dependence: Comparison of Three Medication Dosing Regimens
Lead Sponsor:
National Institute on Drug Abuse (NIDA)
Conditions:
Heroin Dependence
Opioid-Related Disorders
Eligibility:
All Genders
25-55 years
Phase:
PHASE2
Brief Summary
Heroin dependence remains a major addiction problem in the United States. The purpose of this study is to determine the effectiveness of levoacetyl methadol (ORLAAM) in treating heroin dependent indiv...
Detailed Description
Heroin is a highly addictive drug, and its abuse has both medical and social consequences. ORLAAM is approved to treat both opiate and narcotic dependence. The purpose of this study is to determine th...
Eligibility Criteria
Inclusion
- Current opiate dependence
- Provides acceptable proof of identity
- History of 5 or more years of regular heroin use or dependence
- Reads and writes English
Exclusion
- Significant suicidal or homicidal ideation, intent, or plan
- Current AXIS I psychotic, depressive, or anxiety disorder
- Meets DSM-IV criteria for dependence on any drug other than nicotine
- Impending legal complications or incarceration
- On parole or probation that requires reports of drug use or research data
- Currently receiving treatment for opiate dependence
- Currently participating in a 12-step substance detoxification program
- Medical condition that contraindicates administration of ORLAAM
- Plans to leave Houston, Texas within the year following study entry
- Pregnant or breastfeeding
- History of heart problems, including heart arrhythmias
- Requires psychotropic medications (e.g., antidepressants, antipsychotics, anxiolytics)
Key Trial Info
Start Date :
November 1 2001
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2005
Estimated Enrollment :
142 Patients enrolled
Trial Details
Trial ID
NCT00218127
Start Date
November 1 2001
End Date
July 1 2005
Last Update
January 12 2017
Active Locations (1)
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1
Department of Psychatiry, Mental Services
Houston, Texas, United States, 77030