Status:
COMPLETED
Evaluating Responses to Drug-Related Cues Versus Neutral Cues to Understand the Effects of Marijuana Craving - 1
Lead Sponsor:
Wayne State University
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Marijuana Abuse
Eligibility:
All Genders
21-45 years
Brief Summary
The majority of past research on marijuana treatment has specifically targeted the alleviation of withdrawal symptoms. Minimal focus has been placed on how altering craving effects may play a role in ...
Detailed Description
Marijuana is the most commonly used illegal drug in the United States; more than 2 million Americans either abuse or are dependent on the drug. The development of a medication to reduce marijuana use ...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Meets DSM-IV diagnosis criteria for marijuana dependence. Participants enrolled in the control group should not meet DSM-IV diagnosis criteria for any Axis I disorder, and should not use marijuana or have had limited marijuana exposure.
- Reads and writes English
- If female, willing to use adequate contraception throughout the study
- Exclusion criteria:
- Meets DSM-IV diagnosis criteria for a psychiatric illness
- History of a psychotic disorder
- Seeking treatment for marijuana dependence
- Neurologic disease, including structural brain abnormalities (e.g., neoplasms), stroke, seizures, infectious disease, head trauma resulting in unconsciousness, or evidence of neurologic illness resulting from HIV/AIDS
- Cardiovascular disease, including edema, chest pain or palpitations after exertion or drug use, myocardial infarction (heart attack), systolic blood pressure greater than 160 mmHg or less than 95 mmHg, or diastolic blood pressure greater than 95 mmHg
- Pulmonary disease, including apnea, cor pulmonale, tuberculosis, dyspnea, orthopnea, or tachypnea
- Systemic disease, including endocrinopathies, kidney or liver failure, hypothyroidism, adrenocortical insufficiency, or an autoimmune disease involving the central nervous system
- Currently dependent on any drug other than marijuana or nicotine
- Cognitively impaired
- Pregnant or breastfeeding
Exclusion
Key Trial Info
Start Date :
September 1 2004
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2008
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00218478
Start Date
September 1 2004
End Date
July 1 2008
Last Update
June 5 2012
Active Locations (1)
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1
Wayne State University
Detroit, Michigan, United States, 48207