Status:
COMPLETED
Cognitive Behavior Therapy and Habit Reversal Training for the Treatment of Chronic Tic Disorders in Children
Lead Sponsor:
Tourette Association of America
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Tourette Syndrome
Tic Disorders
Eligibility:
All Genders
9-17 years
Phase:
PHASE2
PHASE3
Brief Summary
This study will determine the effectiveness of cognitive behavior therapy (CBT) with habit reversal training (HRT) in treating chronic tic disorders (CTDs) in children and adolescents.
Detailed Description
CTDs and Tourette syndrome are neurobehavioral disorders that are characterized by a persistent pattern of motor and vocal tics. Tics are intermittent movements or sounds that occur repeatedly. They c...
Eligibility Criteria
Inclusion
- Meets DSM-IV diagnostic criteria for chronic tic disorder (chronic motor or vocal tic disorder or Tourette syndrome)
- Score of at least 3 on the Clinical Global Impressions Severity Scale
- Score of at least 14 on the Yale Global Tic Severity Scale (YGTSS) or at least 10 for individuals with motor tics only
- Unmedicated or currently on a stable medication treatment for tics, obsessive compulsive disorder (OCD), ADHD, anxiety, and/or depressive disorder for at least 6 weeks, with no planned changes for the duration of study participation
- Child speaks English
Exclusion
- Score greater than 30 on the YGTSS
- IQ less than 80 on the Wechsler Abbreviated Scale of Intelligence (WASI)
- Meets DSM-IV criteria for substance abuse or dependence within the 3 months prior to study entry
- Meets DSM-IV criteria for conduct disorder within the 3 months prior to study entry
- Lifetime DSM-IV diagnosis of pervasive developmental disorder, mania, or psychotic disorder
- Any serious psychiatric, psychosocial, or neurological condition (i.e., OCD, ADHD, major depressive disorder, anxiety, severe aggression, or family discord) requiring immediate treatment other than what is provided in the current study (i.e., medication, school intervention, or family therapy)
- Previous treatment with four or more sessions of HRT for tics
Key Trial Info
Start Date :
December 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2007
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00218777
Start Date
December 1 2004
End Date
May 1 2007
Last Update
December 14 2015
Active Locations (3)
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1
UCLA Child OCD, Anxiety, and Tic Disorders Program
Los Angeles, California, United States, 90402
2
Johns Hopkins University
Baltimore, Maryland, United States, 21287
3
University of Wisconsin-Milwaukee
Milwaukee, Wisconsin, United States, 53211