Status:

TERMINATED

Dilantin Levels With Continuous Delivery of Enteral Feedings - A Pilot Study

Lead Sponsor:

Penn State University

Conditions:

Seizures

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

It is unclear how enteral nutrition via a feeding tube should be given when a patient is receiving enteral Dilantin. Some caregivers hold the feedings for one hour before and one hour after the Dilant...

Detailed Description

Rationale: It is unclear how enteral nutrition via feeding tube should be given when a patient is receiving enteral Dilantin. Some caregivers hold the feedings for one hour before and one hour after t...

Eligibility Criteria

Inclusion

  • On Dilantin for seizure prophylaxis (dose determined by primary caregiver) with therapeutic Dilantin levels
  • Receiving enteral nutrition by the interrupted method at goal feeding rate
  • Age \>18
  • Feeding tube in proper position, no restriction as to type of feeding tube (nasogastric, nasoduodenal, gastrostomy, jejunostomy), but both Dilantin and enteral feeding must be given through the same tube

Exclusion

  • History of seizures
  • Albumin infusions necessary during study period
  • Anticipation that feedings will need to be held for more than 4 hours at a time
  • Patients that do not maintain stable Dilantin levels (\< 25% variability) with the interrupted method of feeding
  • Inability to obtain consent from patient or spokesperson

Key Trial Info

Start Date :

August 1 1997

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2007

Estimated Enrollment :

3 Patients enrolled

Trial Details

Trial ID

NCT00219479

Start Date

August 1 1997

End Date

December 1 2007

Last Update

November 24 2017

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