Status:

UNKNOWN

Clinical and Molecular Characterization of Familial Microsatellite Stable Colorectal Cancer

Lead Sponsor:

Radboud University Medical Center

Conditions:

Colorectal Neoplasms

Eligibility:

All Genders

Up to 51 years

Brief Summary

Two major genetic pathways leading to colorectal carcinoma can well be distinguished; the 'suppressor pathway', which is characterized by inactivation of tumor-suppressor genes and the 'mutator pathwa...

Detailed Description

Patients with familial colorectal cancer will be characterized with respect to family history, medical history and demographic characteristics. The histopathology of the tumors will be reviewed. Tumor...

Eligibility Criteria

Inclusion

  • \- Colorectal cancer before the age of 51 years
  • Microsatellite stable tumor

Exclusion

  • \-

Key Trial Info

Start Date :

March 1 2004

Trial Type :

OBSERVATIONAL

End Date :

September 1 2008

Estimated Enrollment :

130 Patients enrolled

Trial Details

Trial ID

NCT00220246

Start Date

March 1 2004

End Date

September 1 2008

Last Update

March 1 2007

Active Locations (1)

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1

Radboud University

Nijmegen, Netherlands