Status:
COMPLETED
Polymorphism of the Cytochrome P450-system in Renal Transplants
Lead Sponsor:
University Hospital Schleswig-Holstein
Collaborating Sponsors:
University of Kiel
Conditions:
Function of Renal Transplant
Eligibility:
All Genders
18-70 years
Brief Summary
In this study the researchers want to investigate genetic polymorphisms of cytochrome 450 enzymes and the multiple drug resistance (MDR) gene in renal transplant patients to look for differences in do...
Detailed Description
Primary endpoint is the 1. serum creatinine in patients with and without polymorphysms 2. rate of rejections in patients with and without polymorphysms
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Renal transplant patients receiving one or more of the following drugs:
- tacrolimus
- sirolimus
- everolimus
- cyclosporin A
- fluvastatin
- Informed consent given by the patient
Exclusion
Key Trial Info
Start Date :
March 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2006
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00223054
Start Date
March 1 2005
End Date
October 1 2006
Last Update
August 4 2011
Active Locations (1)
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1
University of Schleswig-Holstein, Campus Kiel, Department of Nephrology
Kiel, Germany, 24105