Status:
COMPLETED
An Add-On Trial of Quetiapine in Patients With Bipolar Disorder and Cocaine Dependence
Lead Sponsor:
University of Texas Southwestern Medical Center
Conditions:
Bipolar Disorder
Cocaine Dependence
Eligibility:
All Genders
18-60 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine if quetiapine add-on therapy is associated with a decrease in cocaine use and craving and a greater improvement in mood.
Detailed Description
One Hundred (100) outpatients with a diagnosis of bipolar I disorder and cocaine abuse/dependence, established by a structured clinical interview and confirmed by a psychiatrist, will participate. Eli...
Eligibility Criteria
Inclusion
- Bipolar Disorder, type I; Cocaine Dependence with use in the past 7 days; Currently taking a mood stabilizer; Meets criteria for a hypomanic or manic episode
Exclusion
- Bipolar Disorder, type II, NOS; Cyclothymia; Other substance dependence; Diabetes; Initiated therapy in the past 2 weeks; History of cataracts or likely cataracts; Current active suicidal or homicidal ideation; Life threatening medical condition; Mental retardation, dementia or severe cognitive impairment; Pregnant or nursing womenon; antipsychotic within 7 days of beginning Quetiapine therapy or have initiated antidepressants or mood stabilizers or psychotherapy within the past two weeks.
Key Trial Info
Start Date :
November 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2007
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00223210
Start Date
November 1 2005
End Date
December 1 2007
Last Update
August 20 2012
Active Locations (1)
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1
The University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, United States, 75390