Status:
COMPLETED
Quetiapine in Patients With Bipolar and Alcohol Abuse/Dependence
Lead Sponsor:
University of Texas Southwestern Medical Center
Conditions:
Bipolar Disorder
Alcohol Abuse/Dependence
Eligibility:
All Genders
18-70 years
Phase:
PHASE4
Brief Summary
The abuse of alcohol is especially common in people with bipolar disorder. However, very little is known about the pharmacotherapy of people with both bipolar disorder and alcohol abuse/dependence. Th...
Detailed Description
Experimental: After obtaining informed consent, 100 patients with bipolar I, or II disorders and alcohol abuse/dependence confirmed by a structured clinical interview (SCID) will be enrolled. from ref...
Eligibility Criteria
Inclusion
- Bipolar I or II
- Ages 18-70
Exclusion
- Life threatening medical condition causing participation in the study hazardous
- Alcohol abuse within the past 2 weeks
- History of cataracts or likely cataracts on baseline eye exam
- History of hepatic cirrhosis or AST or ALT more than three times normal limit
- Current active suicidal or homicidal ideation
- History of allergic reaction, poor response or intolerable side effects to quetiapine
- Antipsychotic use within 7 days of beginning quetiapine therapy
- Mental retardation, dementia or other severe cognitive impairment
Key Trial Info
Start Date :
November 1 2002
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2004
Estimated Enrollment :
115 Patients enrolled
Trial Details
Trial ID
NCT00223249
Start Date
November 1 2002
End Date
August 1 2004
Last Update
April 4 2016
Active Locations (1)
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1
The UT Southwestern Medical Center at Dallas
Dallas, Texas, United States, 75390-8843