Status:

COMPLETED

Evaluation of Lungs of Normal Individuals by Lung Lavage, Brushing and Bronchial Wall Biopsy

Lead Sponsor:

Weill Medical College of Cornell University

Collaborating Sponsors:

New York Presbyterian Hospital

Rockefeller University

Conditions:

Smoking

Lung Diseases

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to obtain biologic materials from the blood and lungs of normal individuals to establish a set of normal range for various parameters. These will provide important informa...

Detailed Description

Study procedures will be performed at the Weill Cornell Medical College-New York Presbyterian Hospital and/or Weill Greenburg York Avenue Building. Study procedures done elsewhere that are within the ...

Eligibility Criteria

Inclusion

  • All study subjects should be able to provide informed consent
  • Males or females ages 18 years and older.
  • Must provide HIV informed consent.
  • Non-smokers, ex-smokers and smokers.

Exclusion

  • Individuals not deemed in good overall health by the investigator will not be accepted into the study.
  • Drug and/or alcohol abuse within the past six months.
  • Individuals with history of chronic lung disease, including asthma or with recurrent or recent (within three months) acute pulmonary disease will not be accepted into the study.
  • Individuals with allergies to atropine or any local anesthetic will not be accepted into the study.
  • Individuals with allergies to pilocarpine, isoproterenol, terbutaline, atropine or aminophylline will not be accepted into the study
  • Females who are pregnant or nursing will not be accepted into the study

Key Trial Info

Start Date :

January 1 2004

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 1 2012

Estimated Enrollment :

196 Patients enrolled

Trial Details

Trial ID

NCT00224185

Start Date

January 1 2004

End Date

September 1 2012

Last Update

May 2 2016

Active Locations (1)

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Department of Genetic Medicine, WMC of Cornell Univeristy

New York, New York, United States, 10021