Status:
COMPLETED
Clozapine-Augmentation With Ziprasidone or Risperidone, a Randomized, Prospective Trial
Lead Sponsor:
Central Institute of Mental Health, Mannheim
Conditions:
Schizophrenia, Schizoaffective Disorder
Eligibility:
All Genders
18-70 years
Phase:
PHASE4
Brief Summary
We aim to compare the augmentation of clozapine with ziprasidone or risperidone in a randomized, prospective manner.
Detailed Description
Partial response of schizophrenic psychoses to a monotherapy with clozapine is a frequent problem of clinical psychiatry. Current problems are treatment resistant positive and/or negative symptoms, as...
Eligibility Criteria
Inclusion
- Treatment resistant schizophrenic or schizoaffective disorder under therapy with clozapine,
- Age between 18 and 70,
- Informed consent
Exclusion
- No informed consent,
- Intolerance with respect to ziprasidone or risperidone,
- Contraindications with respect to these substances,
- Gravidity or missing anticonceptive safety
- Substance dependance (excluded nicotin)
Key Trial Info
Start Date :
November 1 2003
Trial Type :
INTERVENTIONAL
End Date :
September 1 2006
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00224315
Start Date
November 1 2003
End Date
September 1 2006
Last Update
June 4 2008
Active Locations (1)
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1
Central Institute of Mental Health, Department of Psychiatry,
Mannheim, Baden-Wurttemberg, Germany, 68159