Status:
COMPLETED
Bone Marrow Transfer to Enhance ST-Elevation Infarct Regeneration
Lead Sponsor:
Hannover Medical School
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
18+ years
Phase:
PHASE1
Brief Summary
After successful percutaneous coronary intervention (PCI) for acute ST-segment elevation myocardial infarction, 60 patients were randomly assigned to either a control group (n=30) that received optimu...
Detailed Description
Emerging evidence suggests that stem cells and progenitor cells derived from bone marrow can be used to improve cardiac function in patients after acute myocardial infarction. In this randomised trial...
Eligibility Criteria
Inclusion
- Patients were eligible if they were admitted within 5 days of the onset of symptoms of a first ST-segment elevation myocardial infarction
- Had undergone successful PCI with stent implantation in the infarctrelated artery
- Had hypokinesia or akinesia involving more than two thirds of the left-ventricular anteroseptal, lateral, and/or inferior wall, as shown by angiography done immediately after PCI.
Exclusion
- We excluded patients who had multivessel coronary artery disease, pulmonary edema, cardiogenic shock, advanced renal or hepatic dysfunction, or documented terminal illness or cancer.
Key Trial Info
Start Date :
January 1 2002
Trial Type :
INTERVENTIONAL
End Date :
October 1 2003
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00224536
Start Date
January 1 2002
End Date
October 1 2003
Last Update
September 23 2005
Active Locations (1)
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1
Hannover Medical School
Hanover, Germany, 30625