Status:
COMPLETED
Zinc Supplementation in Cholera Patients
Lead Sponsor:
International Centre for Diarrhoeal Disease Research, Bangladesh
Collaborating Sponsors:
Thrasher Research Fund
World Bank
Conditions:
Cholera
Eligibility:
All Genders
3-14 years
Phase:
PHASE3
Brief Summary
Cholera is one of the leading causes of morbidity and mortality among children and adult in developing countries. We will evaluate the effect of supplementation of zinc on reduction of duration and se...
Detailed Description
Study design: A double blind randomized clinical trial using zinc and placebo. Randomization: Patients will be randomized to one of two groups, A or B. Block randomization will be done using block ...
Eligibility Criteria
Inclusion
- Children aged between 3-14 years hospitalized at ICDDR, B presenting with cholera within 24 hours of onset.
- Stool output more than 4ml/kg/hour within the first 6 hours of observation period.
- Positive dark field examination
Exclusion
- Unable to rehydrate within 6 hours
- Negative dark field examination
- Systemic illness requiring immediate administration of antibiotics.
- Received antibiotics in the 24 hours prior to hospitalization
- Patients presenting with bloody mucoid diarrhea
- Unconscious or medical emergencies
Key Trial Info
Start Date :
November 1 2000
Trial Type :
INTERVENTIONAL
End Date :
July 1 2002
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00226616
Start Date
November 1 2000
End Date
July 1 2002
Last Update
October 20 2005
Active Locations (2)
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1
ICDDR,B, Dhaka hospital
Dhaka, Bangladesh, 1000
2
S.k.Roy
Dhaka, Bangladesh, 1000