Status:
COMPLETED
Antidepressant Medication for Reducing HIV Risk Behavior in Depressed Intravenous Drug Users
Lead Sponsor:
Butler Hospital
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Depression
Substance-Related Disorders
Eligibility:
All Genders
18-75 years
Phase:
PHASE3
Brief Summary
This study will evaluate the effectiveness of antidepressant medication treatment in reducing HIV risk behaviors in intravenous drug users with depression.
Detailed Description
Depression and injection drug use often come hand-in-hand. This is especially true in populations with limited access to mental health care and with a high risk of illness and HIV transmission. Depres...
Eligibility Criteria
Inclusion
- DSM-IV diagnosis of major depression, dysthymia, substance-induced major depression, or major depression plus dysthymia
- Score of greater than 14 on the Hamilton Rating Scale for Depression
- Current opiate or cocaine use
- History of injection equipment sharing
- English-speaking
Exclusion
- History of injection equipment sharing within 6 months of study entry
- Currently at risk for suicide
- Currently experiencing symptoms of psychosis
- Currently taking any other psychotropic medication
- Diagnosed with bipolar disorder, schizophrenia, schizoaffective disorder, schizophreniform disorder, or paranoid disorder
- Informed that treatment with antidepressant medications is medically inadvisable
- Pregnant
Key Trial Info
Start Date :
September 1 2000
Trial Type :
INTERVENTIONAL
End Date :
September 1 2004
Estimated Enrollment :
265 Patients enrolled
Trial Details
Trial ID
NCT00228007
Start Date
September 1 2000
End Date
September 1 2004
Last Update
August 22 2013
Active Locations (1)
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1
Rhode Island Hospital
Providence, Rhode Island, United States, 02903