Status:
COMPLETED
The Effect of Aerobic Exercise on Learning After Stroke
Lead Sponsor:
University of Kansas
Collaborating Sponsors:
American Heart Association
Conditions:
Stroke
Eligibility:
All Genders
18-85 years
Phase:
PHASE1
Brief Summary
Determine if attaining aerobic fitness is beneficial in producing cortical neuroplasticity in individuals with chronic stroke.
Detailed Description
Crossover clinical trial. Experimental group undergoes 3x/wk/6 months of aerobic conditioning. Control group performs usual daily activities. All participants will be assessed with cognitive and motor...
Eligibility Criteria
Inclusion
- Single ischemic stroke occuring 6-72 months prior
- Fugl-Meyer score (upper + lower extremity) 45 or greater
- Mini mental status score of \>23
- approval of the subject's medical doctor
Exclusion
- already performing \>20 min of cardiovascular exercise 3x/wk or more
- alcohol consumption of \>2 oz. liquor, 8 oz. wine or 24 oz beer/day
- cardiac history of unstable angina, recent myocardia infarction within the last 3 months, congestive heart failure, significant valve dysfunction
- medical history of recent hospitalization (\> 3 months) for medical illness
- symptomatic peripheral arterial occlusive disease
- orthopedic or chronic pain conditions restricting exercise
- pulmonary or renal failure
- active cancer
- unstable hypertension (\>160/100 mmHg)
- diabetes mellitus (fasting glucose \> 180 NG./dk, HgA1C \> 10%) that is unable to be controlled \< month
- receptive or expressive aphasia as indicated on MMSE
- multiple strokes or other neuromuscular conditions
- major depression that is untreated using the Beck depression inventory
Key Trial Info
Start Date :
September 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2009
Estimated Enrollment :
38 Patients enrolled
Trial Details
Trial ID
NCT00228306
Start Date
September 1 2005
End Date
December 1 2009
Last Update
May 1 2012
Active Locations (1)
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1
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160