Status:
TERMINATED
The Significance of Glucose Intolerance in the Pathogenesis of Idiopathic Axonal Polyneuropathy
Lead Sponsor:
University of Chicago
Conditions:
Idiopathic Axonal Polyneuropathy
Abnormal OGTT
Eligibility:
All Genders
50-75 years
Phase:
PHASE1
Brief Summary
The purpose of this study is to determine whether impaired glucose handling (abnormality in the way the body processes blood sugar) can cause a neuropathy (damage to the nerves).
Detailed Description
Neuropathy of undetermined etiology is a common disease that usually starts at the sixth to seventh decades. It can cause significant pain and disability. Previous studies have demonstrated increased ...
Eligibility Criteria
Inclusion
- Inclusion criteria (for the subjects) will include peripheral neuropathy, age more than 50 years, and a negative workup for neuropathy (aside from an abnormal OGTT). Age matched controls will have no history of diabetes or baseline retinal disease . A workup to rule out other causes of peripheral neuropathy, and an OGTT, will be performed prior to participation in the study.
Exclusion
- Patients with abnormal OGTT in the diabetic range will not be included.
Key Trial Info
Start Date :
January 1 2004
Trial Type :
INTERVENTIONAL
End Date :
January 1 2005
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00228345
Start Date
January 1 2004
End Date
January 1 2005
Last Update
September 5 2013
Active Locations (1)
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1
University of Chicago
Chicago, Illinois, United States, 60637