Status:

UNKNOWN

Study of Heat Shock Proteins as Prognostic Factor of Acute Renal Failure in Children (HSP-Study)

Lead Sponsor:

University of Munich Children's Clinic

Collaborating Sponsors:

Ludwig-Maximilians - University of Munich

Conditions:

Kidney Failure, Acute

Eligibility:

All Genders

Up to 18 years

Brief Summary

The purpose of the investigators' study is to determine whether the production of heat shock proteins has an effect on the development and the outcome of acute renal failure in children.

Detailed Description

A prognostic factor for the development of acute renal failure (ANR) in children would be very valuable for therapy regulation. So-called chaperones out of the family of heat shock proteins (HSP) are ...

Eligibility Criteria

Inclusion

  • Between 0 and 18 years of age.
  • Either severe sepsis, shock of any origin or asphyxia.
  • Operated patients with operative or post-operative transfusion requirement of at least 0.5 x 80 ml/kg body weight of erythrocyte concentrate.

Exclusion

  • Existing affection of the kidney.
  • Kidney transplantation.
  • Missing written consent of the parents or guardian (if applicable).

Key Trial Info

Start Date :

October 1 2005

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2010

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT00230412

Start Date

October 1 2005

End Date

December 1 2010

Last Update

February 2 2010

Active Locations (6)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 2 (6 locations)

1

Klinikum Augsburg, II. Klinik für Kinder und Jugendliche

Augsburg, Bavaria, Germany, 86156

2

Kinderklinik Memmingen

Memmingen, Bavaria, Germany, 87700

3

Klinikum der Universität München, Kinderklinik und Poliklinik im Dr. von Haunerschen Kinderspital

Munich, Bavaria, Germany, 80337

4

Deutsches Herzzentrum München

Munich, Bavaria, Germany, 80636