Status:
COMPLETED
External Beam Radiation Therapy - Target Volume
Lead Sponsor:
University Health Network, Toronto
Collaborating Sponsors:
Princess Margaret Hospital, Canada
Conditions:
Prostatic Neoplasms
Eligibility:
MALE
18+ years
Phase:
PHASE2
Brief Summary
Delivery of conformal radiation therapy following radical prostatectomy is limited by the inability to define the clinical target volume (CTV). This stems from a poor understanding of patterns of loca...
Eligibility Criteria
Inclusion
- Patients following radical prostatectomy for prostate adenocarcinoma with one or more of the following adverse features:
- pT2 + positive surgical margins ) pT3 ) PSA ≤ 2ng/ml Persistently elevated PSA at 3 months )
- Patients with initially undetectable PSA following prostatectomy for prostate adenocarcinoma with subsequent PSA relapse
- Patients being planned for radiation therapy
- No evidence of distant metastases
- Age ≥ 18 years
- ECOG performance status 0 or 1
- Informed consent
Exclusion
- Contraindications to MRI Patients weighing \>136 kgs (weight limit for the scanner tables) Patients with pacemakers, cerebral aneurysm clips, shrapnel injury or implantable electronic devices not compatible with MRI.
- Severe claustrophobia
- Inflammatory bowel disease or collagen vascular disease
- Previous colorectal surgery
- Previous pelvic radiotherapy
Key Trial Info
Start Date :
January 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2013
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT00230438
Start Date
January 1 2005
End Date
May 1 2013
Last Update
January 6 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Princess Margaret Hospital
Toronto, Ontario, Canada, M5G 2M9