Status:

COMPLETED

Thyroid Hormone Dose Adjustment in Pregnancy

Lead Sponsor:

Brigham and Women's Hospital

Collaborating Sponsors:

Harvard Medical School (HMS and HSDM)

Conditions:

Pregnancy

Hypothyroidism

Eligibility:

FEMALE

Phase:

NA

Brief Summary

Our aim is to compare the safety and efficacy of 2 different empiric levothyroxine dose adjustment recommendations to be made at the first confirmation of pregnancy in women with a history of hypothyr...

Detailed Description

Our aim is to compare the safety and efficacy of 2 different empiric levothyroxine dose adjustment recommendations to be made at the first confirmation of pregnancy in women with a history of hypothyr...

Eligibility Criteria

Inclusion

  • women with a prior diagnosis of hypothyroidism, currently receiving levothyroxine therapy
  • less than 8 weeks pregnant

Exclusion

  • cardiac disease, renal failure
  • not euthyroid biochemically within 6 months pre-pregnancy

Key Trial Info

Start Date :

July 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2010

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT00230802

Start Date

July 1 2005

End Date

July 1 2010

Last Update

December 23 2016

Active Locations (1)

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1

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02115