Status:
COMPLETED
Molecular Genetics of Retinal Degenerations
Lead Sponsor:
National Eye Institute (NEI)
Conditions:
Retinal Degeneration
Retinitis Pigmentosa
Eligibility:
All Genders
4+ years
Brief Summary
This multinational study will investigate the inheritance of genetic retinal degeneration in families of different nationalities and ethnic backgrounds in order to identify the genes that, when altere...
Detailed Description
Objective: This project, Molecular Genetics of Retinal Degenerations will study the inheritance of genetic retinal degenerations, both Mendelian and complex, in families of many nationalities and ethn...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Patients that meet diagnostic criteria for specific retinal degenerations will be recruited from the NEI and collaborating clinics.
- Subjects with the following will be recruited:
- Individuals or family members of individuals with Retinal degenerations, either congenital, childhood, or age related.
- Adults must be capable of providing their own consent.
- All subjects must be able to cooperate with study examination and phlebotomy.
- Older than 4 years of age.
- EXCLUSION CRITERIA:
- Diseases, infections, or trauma that mimic primary retinal degenerations.
- Children requiring sedation for study procedures.
Exclusion
Key Trial Info
Start Date :
September 26 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 23 2016
Estimated Enrollment :
3549 Patients enrolled
Trial Details
Trial ID
NCT00231010
Start Date
September 26 2005
End Date
June 23 2016
Last Update
April 5 2018
Active Locations (6)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892
2
Harvard Medical School
Boston, Massachusetts, United States, 02115
3
Cleveland Clinic Foundation Childrens Hospital
Cleveland, Ohio, United States, 44195
4
Sun Yat-Sen University
Guangzhou, China, 510275