Status:
COMPLETED
Effectiveness of Behavior Therapy and Psychosocial Therapy for the Treatment of Tourette Syndrome and Chronic Tic Disorder
Lead Sponsor:
Massachusetts General Hospital
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Tourette Syndrome
Tic Disorders
Eligibility:
All Genders
16+ years
Phase:
PHASE2
Brief Summary
This study will compare the efficacy of supportive therapy versus habit-reversal therapy for the treatment of Tourette syndrome and chronic tic disorder.
Detailed Description
Tourette syndrome and chronic tic disorder are neurological disorders characterized by tics. Tics are involuntary, rapid motor movements or vocalizations that occur suddenly and repeatedly. In adults,...
Eligibility Criteria
Inclusion
- Meets DSM-IV diagnostic criteria for Tourette syndrome or chronic tic disorder
- The primary reason for seeking treatment is Tourette syndrome and/or chronic tic disorder
- Either Tourette syndrome or chronic tic disorder is of more concern than any other simultaneous disease or disorder
- Score greater than 3 on the Clinical Global Impressions Severity Scale
- Score greater than 14 on the Yale Global Tic Severity Scale
- Unmedicated or on stable medication treatment for tics, obsessive compulsive disorder, attention deficit hyperactivity disorder, and/or depressive disorder for at least 6 weeks, and not planning to change medication for the duration of study participation
Exclusion
- Total tic score greater than 33
- Score less than 80 on the Wechsler Test of Adult Reading
- DSM-IV diagnosis of alcohol or substance dependence within the 3 months prior to study enrollment
- Currently taking psychotropic medications for any psychiatric disorder (except for tics, obsessive compulsive disorder, attention deficit hyperactivity disorder, and/or depressive disorder)
- Any serious psychiatric disorder (e.g., bipolar disorder, psychosis) that requires immediate alternative treatment
- Previously treated with four or more sessions of habit-reversal therapy for tics
Key Trial Info
Start Date :
October 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2010
Estimated Enrollment :
122 Patients enrolled
Trial Details
Trial ID
NCT00231985
Start Date
October 1 2005
End Date
March 1 2010
Last Update
February 9 2012
Active Locations (3)
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1
Yale Child Study Center, Yale University
New Haven, Connecticut, United States, 06520-7900
2
OCD Clinic/Psychiatry, Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
3
University of Texas Health Sciences Center
San Antonio, Texas, United States, 78229-3900