Status:
COMPLETED
Cyberknife Radiosurgery for Locally Advanced Pancreatic Cancer
Lead Sponsor:
Stanford University
Conditions:
Pancreatic Cancer
Eligibility:
All Genders
18-90 years
Phase:
PHASE2
Brief Summary
The purpose of the trial is to test the efficacy of combining conventional chemoradiotherapy with radiosurgery for locally advanced pancreas cancer.
Detailed Description
The purpose of the trial is to test the efficacy of treating locally advanced pancreatic cancer with 5FU and concurrent conventional radiotherapy followed by precisely administered single fraction of ...
Eligibility Criteria
Inclusion
- Pancreatic tumors not to exceed 7.5 cm.
- Histologically confirmed malignancies of the pancreas, (ampulla of Vater or periampullary duodenum, tumors may be included when the head of pancreas is secondarily involved and unresectable criteria are met).
- Unresectable by CT criteria or unresectable at exploratory laparotomy or laparoscopy. CT criteria for unresectability include encasement of the superior mesenteric vein (SMV), portal vein (PV) or invasion of the celiac artery or superior mesenteric artery (SMA).
- Patients with metastatic disease may be treated if they are symptomatic from the primary tumor.
- Eastern Clinical Oncology Group performance status 0, 1 or 2.
Exclusion
- Chemotherapy within 1 month of registration.
Key Trial Info
Start Date :
July 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2007
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00233415
Start Date
July 1 2003
End Date
May 1 2007
Last Update
June 2 2010
Active Locations (1)
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1
Stanford University School of Medicine
Stanford, California, United States, 94305